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Rory
Post  Post subject: Ebola vaccine  |  Posted: Mon Feb 02, 2015 10:41 pm
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So GSK and another pharma have initiated trials of the Ebola vaccine in Liberia. But how are they going to prove causation between administering the vaccine and protection from Ebola? Ethically it is not possible to forcibly expose the vaccine recipients to the virus, which means that any vaccine recipient who does not contract Ebola might have been protected by the vaccine, or might just have never encountered the virus - AFAICT the best that they can do is to present a very strong association.

I wonder if pharma companies would actually intentionally plant a virus and initiate an outbreak in order to engineer the market demand for a treatment or vaccine - for profit's sake? :evil:

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Robittybob1
Post  Post subject: Re: Ebola vaccine  |  Posted: Thu Feb 05, 2015 5:51 am

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Rory wrote:
So GSK and another pharma have initiated trials of the Ebola vaccine in Liberia. But how are they going to prove causation between administering the vaccine and protection from Ebola? Ethically it is not possible to forcibly expose the vaccine recipients to the virus, which means that any vaccine recipient who does not contract Ebola might have been protected by the vaccine, or might just have never encountered the virus - AFAICT the best that they can do is to present a very strong association.

I wonder if pharma companies would actually intentionally plant a virus and initiate an outbreak in order to engineer the market demand for a treatment or vaccine - for profit's sake? :evil:

Just be happy they are getting the disease under control.


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marnixR
Post  Post subject: Re: Ebola vaccine  |  Posted: Thu Feb 05, 2015 7:27 am
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Rory wrote:
I wonder if pharma companies would actually intentionally plant a virus and initiate an outbreak in order to engineer the market demand for a treatment or vaccine - for profit's sake? :evil:


surely you can't mean that ? that way lies conspiracy theory country
if anything big pharma was initially not interested in ebola because there's not much money to be made in africa
they'd rather produce a medicine for which they can invent an imaginary disease, or medicalise a normal human condition - a lot easier than finding a cure where controlled trials are not that easy to come by

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billvon
Post  Post subject: Re: Ebola vaccine  |  Posted: Fri Feb 06, 2015 11:13 pm

Joined: Thu Oct 02, 2014 5:23 pm
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Rory wrote:
So GSK and another pharma have initiated trials of the Ebola vaccine in Liberia. But how are they going to prove causation between administering the vaccine and protection from Ebola? Ethically it is not possible to forcibly expose the vaccine recipients to the virus, which means that any vaccine recipient who does not contract Ebola might have been protected by the vaccine, or might just have never encountered the virus - AFAICT the best that they can do is to present a very strong association.

Right. That's how most vaccines are evaluated. There are still areas where Ebola is active, and those areas will likely receive some of the earliest trials of the vaccine. If it works then it moves on to vaccination of healthcare workers (who are regularly exposed as part of their job) and they get a stronger correlation.

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I wonder if pharma companies would actually intentionally plant a virus and initiate an outbreak in order to engineer the market demand for a treatment or vaccine - for profit's sake? :evil:

No.


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Gabriel Filice
Post  Post subject: Re: Ebola vaccine  |  Posted: Sat Mar 04, 2017 3:06 pm

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The researchers also evaluate the amount of antibodies produced against the antigen in the vaccine.
Surely they can't expose people to infection voluntarily. Many vaccines are administered in populations at risk.


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